Tetsuyuki Kitamoto Selected Research

Prions

12/2023	V180I genetic Creutzfeldt-Jakob disease: Severe degeneration of the inferior olivary nucleus in an autopsied patient with identification of the M2T prion strain.
1/2023	A point mutation in GPI-attachment signal peptide accelerates the development of prion disease.
4/2021	Further Characterization of Glycoform-Selective Prions of Variably Protease-Sensitive Prionopathy.
1/2021	Prion Gene PRNP Y162X Truncation Mutation Can Induce a Refractory Esophageal Achalasia.
1/2020	Eliminating transmissibility of bovine spongiform encephalopathy by dry-heat treatment.
1/2019	A Novel Combination of Prion Strain Co-Occurrence in Patients with Sporadic Creutzfeldt-Jakob Disease.
1/2019	A domain responsible for spontaneous conversion of bank vole prion protein.
1/2019	Two distinct prions in fatal familial insomnia and its sporadic form.
1/2019	Intermolecular crosslinking of abnormal prion protein is efficiently induced by a primuline-sensitized photoreaction.
1/2019	Ganglioside Synthase Knockout Reduces Prion Disease Incubation Time in Mouse Models.

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Tetsuyuki Kitamoto Research Topics

Disease

46	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 12/2023 - 06/2002
30	Sporadic Creutzfeldt-Jakob Disease 03/2023 - 12/2003
28	Prion Diseases (Transmissible Spongiform Encephalopathies) 03/2023 - 06/2002
19	Acquired CJD 12/2023 - 12/2003
11	Infections 10/2021 - 06/2002
9	Scrapie 01/2020 - 03/2003
9	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 06/2002
6	Kuru 10/2018 - 08/2006
6	Amyloid Plaque 07/2013 - 12/2003
5	Myoclonus (Nocturnal Myoclonus) 01/2019 - 06/2008
4	Dementia (Dementias) 12/2023 - 10/2002
4	Bovine Spongiform Encephalopathy (Mad Cow Disease) 01/2020 - 10/2009
4	Disease Progression 11/2018 - 06/2008
3	Akinetic Mutism (Coma Vigil) 12/2021 - 06/2014
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 01/2013
3	Gliosis 01/2018 - 11/2005
2	Fatal Familial Insomnia 12/2023 - 01/2019
2	Coinfection 07/2013 - 03/2006
2	Ataxia (Dyssynergia) 10/2011 - 09/2009
2	Neuroblastoma 05/2008 - 08/2003
1	Seizures (Absence Seizure) 06/2023
1	Gerstmann-Straussler-Scheinker Disease 03/2023
1	Respiratory Insufficiency (Respiratory Failure) 12/2021
1	Esophageal Achalasia (Megaesophagus) 01/2021
1	Diabetes Mellitus 08/2019
1	Coronary Artery Disease (Coronary Atherosclerosis) 08/2019
1	Proteostasis Deficiencies 01/2019
1	Photosensitivity Disorders (Photodermatitis) 01/2019
1	Olivary Degeneration 01/2019
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2019
1	Craniocerebral Trauma (Head Injury) 10/2018
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2018
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2018
1	Primary Progressive Nonfluent Aphasia (Progressive Nonfluent Aphasia) 01/2018
1	Hashimoto's encephalitis 11/2017
1	Brain Diseases (Brain Disorder) 01/2017
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 11/2016
1	Motor Neuron Disease (Primary Lateral Sclerosis) 11/2016
1	Chronic Wasting Disease 01/2014
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 10/2013
1	Trigeminal Neuralgia (Tic Douloureux) 10/2013
1	Hemifacial Spasm 10/2013
1	Spastic Paraparesis 09/2009

Drug/Important Bio-Agent (IBA)

71	Prion ProteinsIBA 12/2023 - 06/2002
46	Codon (Codons)IBA 12/2023 - 10/2002
29	PrionsIBA 12/2023 - 06/2002
23	Methionine (L-Methionine)FDA Link 01/2023 - 01/2005
11	Peptide Hydrolases (Proteases)FDA Link 08/2019 - 10/2003
10	Valine (L-Valine)FDA Link 12/2023 - 10/2007
9	Proteins (Proteins, Gene)FDA Link 04/2021 - 06/2007
9	Protein Isoforms (Isoforms)IBA 01/2016 - 06/2002
8	Amyloid (Amyloid Fibrils)IBA 10/2018 - 06/2007
5	Arginine (L-Arginine)FDA Link 01/2023 - 11/2007
3	14-3-3 Proteins (14-3-3 Protein)IBA 12/2023 - 12/2009
3	Isoleucine (L-Isoleucine)FDA Link 12/2023 - 11/2016
3	Biomarkers (Surrogate Marker)IBA 10/2022 - 01/2013
3	AntibodiesIBA 04/2021 - 08/2003
3	Lysine (L-Lysine)FDA Link 11/2018 - 10/2009
2	Endopeptidase K (Proteinase K)IBA 04/2021 - 01/2018
2	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 01/2021 - 01/2020
2	PrPSc ProteinsIBA 06/2019 - 03/2011
2	Glutamic Acid (Glutamate)FDA Link 11/2018 - 08/2015
2	THK5351IBA 01/2018 - 01/2018
2	Growth Hormone (Somatotropin)IBA 01/2018 - 01/2018
2	Phosphopyruvate Hydratase (Enolase)IBA 11/2017 - 12/2009
2	Heparin (Liquaemin)FDA LinkGeneric 01/2016 - 07/2011
2	AluminumIBA 01/2003 - 09/2002
2	IronIBA 01/2003 - 09/2002
1	Protein Sorting Signals (Signal Peptide)IBA 01/2023
1	Glycoproteins (Glycoprotein)IBA 04/2021
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2020
1	VitaminsIBA 01/2019
1	haematoside synthetaseIBA 01/2019
1	Fluorescent Dyes (Fluorescent Probes)IBA 01/2019
1	LipidsIBA 01/2019
1	Aspartic Acid (Aspartate)FDA Link 01/2019
1	(N- acetylneuraminyl)- galactosylglucosylceramide N-acetylgalactosaminyltransferaseIBA 01/2019
1	AsparagineIBA 01/2019
1	ApolipoproteinsIBA 01/2019
1	primulineIBA 01/2019
1	GangliosidesIBA 01/2019
1	Apolipoproteins E (ApoE)IBA 01/2019
1	thioflavin TIBA 01/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2017
1	SteroidsIBA 01/2017
1	DNA-Binding Proteins (DNA Binding Protein)IBA 11/2016
1	Guanidine (Guanidine Nitrate)FDA Link 01/2016
1	Peptides (Polypeptides)IBA 10/2012
1	AntigensIBA 10/2012
1	Lysosomal Membrane ProteinsIBA 01/2010
1	Hormones (Hormone)IBA 10/2009
1	dimemorfan (AT 17)IBA 06/2008

Therapy/Procedure

4	Enteral Nutrition (Feeding, Tube) 12/2021 - 10/2011
3	Blood Transfusion (Blood Transfusions) 11/2009 - 02/2009
3	Operative Surgical Procedures 11/2009 - 02/2009
2	Therapeutics 12/2021 - 01/2017
2	Transplantation 10/2013 - 02/2008
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 08/2019
1	Craniotomy 10/2018
1	Electrodes (Electrode) 10/2009